Starting a business: Earn billion due to collagen extraction from pangasius skin leftover.

Each day has 8 tons of pangasius skin to leave in Vietnam and this is a waste product which sold at a low price. The scientists create the technology to extract collagen from waste things to help to increase the value for the fishery industry.

According to statistics, Vietnam exported 1,3 million tons with the value reached 2 billion USD in 2019.  However, only 30% of the gravitation of fish at the body that used, at that time another 70% at head, skin, bone to become a waste product. Averagely, each pangasius factory spread out 5 to 8 tons of fish skin and leave them outside and make the environmental pollution.

However, the pangasius contains 50% dry matter content as collagen in the total 69% protein. Before reality, Associate Professor Ph.D. Phan Dinh Tuan with his research team at Ho Chi Minh Polytechnic University deploys the method of extracting and detaching collagen from waste fish skin in order to increase the value for the fisheries industry.

The “change the game” technology

According to the report of the organization, the demand for the global collagen market in 2019 estimated about 920 tons, and the scale of the collagen market anticipate reached 7.5 billion USD in 2017, with the double growth speed is 6.4% in the stage from now to 2027.

Vietnam scientists found out the potential from collagen separation at pangasius skin, study and deploy many methods from 2000 but the big part still has many disadvantages and it not really working. The old way makes output product backlog 5% of fat content, while the demand for the market only less than 0,5%.

Associate Professor Ph.D.  Phan Dinh Tuan and his partner “change the game” by pangasius skin extraction technology. The team realized that reducing fat content also reducing collagen content after extract.

The researcher soaking fish skin in 3 types of solvent NaOH, LASNa, and ethanol at the rate 1/10 and the temperature only 4 degrees C, to reject fat content, remove the color as deodorizing the bad smell. This way makes fish skin bulging out, connecting protein with lipid is destroyed lead to fat content separate from the skin. At that time, LASNa prevents the fat content sticky again after disband.

However, when lipid is divided that brought about protein makes the decline concentration of skin, therefore, the team stops soak at a particular stage and then divides another fat part at the next stage. At the next step, Associate Professor Tuan with his partner will extract collagen by axit axetic combine with enzyme pepsin in the temperature from 3 degrees C to 17 degrees C in 24 hours. Finally, NaCL is added to centrifugal to separate coarse collagen.

From the model to reality

The product of coarse collagen is brought to dry at specific conditions, helping to produce finished products with a high molecular weight, no color, no smell, and fat content is very low, suit for the application to make the material for producing cosmetics, food product and medicine.

In addition, when the temperature under 39.5%, collagen is not denatured about the structure so easy to preserve. This method achieves an extraction efficiency of up to 84.81%, helping to avoid wasting input materials, helping to increase the value of pangasius in general and pangasius-processed products in particular.

The study carried out by Associate Professor Tuan’s team, in addition to effectively using discarded products, also helps to determine the effect of the three factors (concentration of acetic acid, pepsin enzyme content, and solvent/skin ratio fish) to collagen extraction performance.

From this conclusion, the team can apply the technology to many other products such as Basa fish due to the close correlation between model and experiment. The method of extracting and refining collagen from pangasius skin by Assoc.Prof.Dr. Phan Dinh Tuan and colleagues at the Polytechnic University – National University of Ho Chi Minh City has been granted the exclusive license by the National Office of Intellectual Property Useful French number 2-0001753.


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